Non-Cached Pages Speed Increase

Actually I am on the way to speed up CS-Cart as fast as possible. Cloudflare+Google Pagespeed Nginx Addon+Memcached are in use.

One big part is the non-cached sites in cs-cart - I am wondering which functionality will not work when the Pages get cached. Could someone let me know his knowledge about it.

Delivering this sites from cache like FastCGI Cache will greately increase the speed, as there is like no serverload anymore. Time-To-First-Byte will be much nicer.

Thank you.